Are people ready for a new Science Fiction or Fantasy show or book series?

I've planned a series of fantasy novels (6 novels) and written, revised, edited and sent the first issue to a publishing house that specialises in e-books and the genre fantasy, the genre of the book, well fantasy/supernatural.

What worries me is that they won't accept my book because the plot is something that I'm certain has never been done before, I checked online for novels with this same plot as well as similar movies and so on. So my question is will it get turned down by publishers and people in general for being too original and out-there or are people looking for that.

My target audience is teen-aged girls like 13 to maybe 15 and here's the basic plot of the series; 7 witches who lived in the magical world/dimension have died and roamed the Earth unintentionally as ghosts after their deaths for several centuries in search of the right hosts so they can go back to the magical world/dimension. But of course there's more too it, the witches all have a supposed not so defeated enemy that has or will soon rise to power again and they need the hosts to draw from their energy to build up enough magic to take them down and according to an obscure prophesy that had been filed away from even longer can't move on until all their old enemies are defeated. They don't even know why they ended up stuck on Earth and of course their situation makes their hosts' lives (7 girls who just started high school really complicated).

Even answers from guys will be apresiated.