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xx_kc_xx asked in HealthOther - Health · 1 decade ago

Opiod use, Restless legs, and Seroquel?

When I use medicines that cross the blood-brain barrier (such as Seroquel, Thorazine, or Haldol) I suffer from terrible, terrible restlessness in my legs and sometimes my arms. It gets so bad that I will pace around for about 6 hours, unable to sit for more than 30 seconds, until I can actually sleep. It always happened with the Haldol and Thorazine, bu I used Seroquel for months before it caused it.

A nurse told me that opiod use can intensify the effect of restlessness that a minority of people experience on these kind of drugs and that is why the seroquel now has this effect, as I am a former heroin addict.

I have not been able to find anything on the internet stating this correlation, so I'm wondering if anyone knows anything about this.

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  • 1 decade ago
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    I get the exact same thing that you are talking about. I have always considered it just RLS, however I also get it in my arms. This only happens when I am on certain medications such as Seroquel, tizanidine, Dramamine, mirtazapine, and a few others.

    The only opioid I have ever used is hydrocodone, and I have never abused it. I actually had the RLS before I even used the hydrocodone.

    I know this doesn't exactly answer you question, but I hope I helped somewhat. If you have any questions please IM or email me =)

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